99mTc-MIBI pinhole SPECT in primary hyperparathyroidism: comparison with conventional SPECT, planar scintigraphy and ultrasonography

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Tc-MIBI PINHOLE SPECT IN PRIMARY HYPERPARATHYROIDISM: COMPARISON WITH CONVENTIONAL SPECT, PLANAR SCINTIGRAPHY AND ULTRASONOGRAPHY

Purpose A pinhole collimator is routinely used to increase the resolution of scintigraphy. This prospective study was conducted to determine the interest of Tc-MIBI pinhole SPECT for the preoperative localization of parathyroid lesions in primary hyperparathyroidism. Methods All patients underwent a neck US, TcO4 and Tc-MIBI planar images, and two consecutive SPECT with a parallel (C-SPECT) and...

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Parathyroid scintigraphy in patients with primary hyperparathyroidism: 99mTc sestamibi SPECT and SPECT/CT.

The clinical diagnosis of primary hyperparathyroidism is based largely on serum laboratory test results, as patients often are asymptomatic. Surgery, often with bilateral exploration of the neck, has been considered the definitive treatment for symptomatic disease. However, given that approximately 90% of cases are due to a single parathyroid adenoma, a better treatment may be the selective sur...

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99mTc-MIBI SPECT/CT imaging contribution in the diagnosis of patients with hyperparathyroidism

Introduction: Hyperparathyroidism is presented with increased parathyroid hormone (PTH) secretion due to hyperfunctioning of one or more of the four parathyroid glands. Primary hyperparathyroidism (p-HPT) can be due to parathyroid adenoma, hyperplasia or carcinoma of the parathyroid gland. Secondary hyperparathyroidism (s-HPT) is usually a response to hypocalcaemia and consecut...

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The usefulness of neck pinhole SPECT as a complementary tool to planar scintigraphy in primary and secondary hyperparathyroidism.

UNLABELLED Pinhole SPECT (P-SPECT) has proven to be a high-resolution and sensitive method in both experimental and clinical studies. In this study, we investigated whether P-SPECT combined with conventional planar scintigraphy can give additional information in hyperfunctioning parathyroid gland detection in both primary hyperparathyroidism (pHPT) and secondary hyperparathyroidism (sHPT) since...

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Lesion based diagnostic performance of dual phase 99mTc-MIBI SPECT/CT imaging and ultrasonography in patients with secondary hyperparathyroidism

BACKGROUND We aimed to evaluate the diagnostic performance of 99mTc-MIBI SPECT/CT and ultrasonography in patients with secondary hyperparathyroidism (SHPT), and explored the factors that affect the diagnostic performance. METHODS 99mTc-MIBI SPECT/CT and ultrasonography were performed in 50 patients with SHPT within 1 month before they underwent surgery. Imaging results were confirmed by the p...

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ژورنال

عنوان ژورنال: European Journal of Nuclear Medicine and Molecular Imaging

سال: 2007

ISSN: 1619-7070,1619-7089

DOI: 10.1007/s00259-007-0625-9